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Updated: Jun 7, 2025

Design and Implementation of an Automated Illuminating, Culturing, and Sampling System for Microbial Optogenetic Applications
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使用单组分融合蛋白对酸盐敏感基因的光遗传控制 在Saccharomyces cerevisiae中

Matthew M Cleere1,2, Kevin H Gardner1,3,4

  • 1Structural Biology Initiative, CUNY Advanced Science Research Center, New York, New York 10031, United States.

ACS synthetic biology
|November 12, 2024
PubMed
概括

研究人员开发了新的光激活转录因子,以精确控制酵母中的基因表达. 这些光遗传工具可以微调细胞功能,并以前所未有的控制来研究生物通路.

关键词:
在 EL222 里面,你会看到 EL222 的样子.这是一个LOV域名.在这种情况下,染色染色素无机酸盐 (Pi) 是一种无机酸盐.视觉遗传学 视觉遗传学转录 转录 是一种转录.酵母酵母是一种酵母.

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Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
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