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相关概念视频

Menopause01:28

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Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
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Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
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Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
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3D Modeling of the Lateral Ventricles and Histological Characterization of Periventricular Tissue in Humans and Mouse
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与年龄相关的皮下灰质体积减少是男性健康大脑衰老的一部分.

Radmila Peric1,2, Igor Romčević3, Milica Mastilović3

  • 1Department of Radiology, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21000, Novi Sad, Serbia. radmila.peric@mf.uns.ac.rs.

Irish journal of medical science
|November 12, 2024
PubMed
概括

在健康的男性中,衰老显著减少皮下灰质体积,特别是在右侧. 这些发现有助于区分正常衰老和神经退行.

关键词:
衰老的衰老 衰老的衰老这就是为什么MRI是MRI.神经成像是一种神经成像.下皮层的灰色物质是什么这是一个体积测量仪.

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科学领域:

  • 神经成像是一种神经成像.
  • 老年学是一门学科.
  • 大脑解剖学 大脑解剖学

背景情况:

  • 全球人口正在老龄化,60岁以上的人口预计到2050年将增加一倍.
  • 35岁以后,大脑体积每年自然下降0.2%,每年减少0.2%.
  • 区分正常衰老和神经退行是至关重要的.

研究的目的:

  • 评估衰老对健康男性皮下灰质的影响.
  • 确定生理衰老的潜在生物标志物.
  • 了解特定大脑结构的与年龄相关的变化.

主要方法:

  • 使用脑磁共振 (3T) 对106名健康男性进行回顾性分析.
  • 使用VolBrain软件对皮下灰质进行体积测量分析.
  • 较年轻 (<35) 和较年长 (>35) 年龄组之间的灰质体积的比较.

主要成果:

  • 年龄组之间总内体积没有显著差异.
  • 核,尾状核,白色球体,面,丘脑和腹腔大脑中显著减少 (p<0.05).
  • 观察到不对称的缩,老年人右侧减少更大.

结论:

  • 男性的健康衰老涉及显著的皮下灰色物质体积减少.
  • 不对称的衰老模式是显而易见的,右侧结构的衰老速度更快.
  • 这些体积变化是区分健康衰老和神经退行性疾病的关键指标.