文化定制的信息和试验注册登记:一个随机临床试验
Kevin B Johnson1,2,3, Stacy L Iannone4, Susan L Furth4,5,6
1Division of Biomedical Informatics, Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Children's Hospital of Philadelphia, Philadelphia.
文化定制的视频并没有增加父母决定将黑人儿童注册在研究登记册中. 然而,货币激励措施显著改善了入学决策,这表明结合方法可能是有益的.
科学领域:
- 临床研究方法论临床研究方法论
- 儿科健康的公平性.
- 临床试验中的健康差异
背景情况:
- 包括黑人儿童在内的边缘化群体在临床试验中代表性不足.
- 有效的招聘策略对于提高研究多样性至关重要.
- 文化定制的材料和激励措施是增强参与的潜在方法.
研究的目的:
- 评估文化定制视频对父母决定将黑人儿童纳入研究登记册的影响.
- 评估定制与通用招聘信息的有效性.
- 确定货币激励对入学决策的影响.
主要方法:
- 一个随机的临床试验在一个城市儿科诊所进行.
- 父母被随机分配观看一段,通用视频或量身定制的视频.
- 后期分析检查了货币激励和入学决策之间的关联.
主要成果:
- 在视频组和对照组之间没有观察到注册决策的显著差异.
- 与非货币激励 (墨笔) 相比,在获得货币激励 (礼品卡) 的群体中,注册决策显著更高.
- 货币激励与更高的入学率有关,即使经过对信任进行调整.
结论:
- 文化定制的视频消息本身并没有改善父母决定将黑人儿童注册在研究登记册中.
- 货币激励似乎在提高入学率方面发挥了重要作用.
- 将文化敏感信息与货币激励相结合,可能是增强儿科临床试验参与的有希望的策略.
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