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Updated: Jun 7, 2025

In Vitro Cultivation Techniques for Modeling Liver Organogenesis, Building Assembloids, and Designing Synthetic Tissues using Human Cell Lines
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NSUN5通过增加SMAD3表达来促进肝细胞癌的进展

Hexu Han1, Chengcheng Zhang2, Wenbo Shi3

  • 1Department of Gastroenterology, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, Jiangsu, 225300, P. R. China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|November 12, 2024
PubMed
概括

肝细胞癌 (HCC) 的进展是由NOP2/SunRNA甲基转移酶5 (NSUN5) 驱动的,它是一种促进转移的瘤基因. NSUN5通过调节基因组甲基化来促进表皮质-介质细胞过渡 (EMT),为HCC提供潜在的治疗点.

关键词:
在EMT中,EMT是EMT.这是NSUN5的5号.在SMAD3中,我们可以看到SMAD3.肝细胞癌 (HCC) 是一种肝细胞癌.转移 转移 转移 转移

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