结肠直肠癌查完成和45至50岁患者的产量:一项观察性研究
Theodore R Levin1, Christopher D Jensen2, Natalia Udaltsova2
1Division of Research, Kaiser Permanente Northern California, Oakland, California, and Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, California (T.R.L.).
Annals of internal medicine
|November 12, 2024
概括
结肠直肠癌 (CRC) 查完成率和产量在45-49岁和50岁的个体中是相似的. 这些发现支持更新的指导方针,建议在45岁开始进行CRC查.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 预防医学 预防医学
背景情况:
- 目前的指导方针建议在45岁开始进行结肠直肠癌 (CRC) 查,这是从以前的50岁开始的转变.
- 关于45-49岁年龄组的查完成率和诊断收益率的数据有限.
研究的目的:
- 为了比较45-49岁患者和50岁患者之间的体免疫化学测试 (FIT) 完成率和产量.
- 评估早期CRC查启动的有效性.
主要方法:
- 一个回顾性队列研究使用凯泽永久的数据进行.
- 分析了2022年1月至9月间分发的FIT套件.
- 结果包括FIT完成,阳性,结肠镜后续检查和癌症检测率.
主要成果:
- 45-49岁年龄组的FIT完成率略高 (38.9%),而50岁年龄组的FIT完成率略高 (37.5%).
- 在年轻人群中,FIT阳性率较低 (3.6%对4.0%),结肠镜随访率相似.
- 腺瘤和先进组织学的检测率相似,结直肠癌的检测率相似 (2.8%对2.7%).
结论:
- 该研究表明,45-49岁和50岁的个人之间的FIT完成率和收益率相似.
- 这些发现支持建议从45岁开始对结直肠癌进行查.
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