通过数字通信增强每日口服PrEP的遵守:系统审查和元分析协议
Julien Brisson1, Mariangela Castro-Arteaga1, Dorothy Apedaile2
1Division of Social and Behavioural Health Sciences, Dalla Lana School of Public Health, University of Toronto, Toronto, Canada.
PloS one
|November 12, 2024
概括
数字通信干预措施,如短信和应用程序,可以改善每日口服预暴露预防 (PrEP) 的遵守,以预防艾滋病毒. 本系统审查协议概述了评估其在高风险人群中的有效性方法.
科学领域:
- 公共卫生 公共卫生
- 预防传染病 预防传染病
- 数字健康干预措施 数字健康干预措施
背景情况:
- 暴露前预防 (PrEP) 对于预防艾滋病毒至关重要.
- 坚持每天口服PrEP是必不可少的,但对许多人来说具有挑战性.
- 目前正在探索数字沟通策略,以改善PrEP的遵守情况.
研究的目的:
- 系统地审查和元分析数字通信干预措施对日常口服PrEP遵守的有效性.
- 为了回答研究问题:数字通信干预措施是否提高了高风险个体的PrEP遵守率?
- 本协议详细说明了计划进行的系统审查和元分析.
主要方法:
- 系统搜索Embase,PubMed,Web of Science和PsycINFO数据库,以及临床试验注册表和灰色文献.
- 包括自2012年以来以英语,法语或西班牙语出版的原始随机对照试验.
- 遵守PRISMA 2020指南,有三名审查员进行系统审查和元分析. 主要结局:每天口服PrEP的坚持,用几率比率来衡量.
主要成果:
- 本章节将介绍系统审查和元分析的发现.
- 结果将侧重于关于PrEP遵守的数字通信干预措施的关联指标 (例如,赔率比率).
- 分析将量化这些干预措施的有效性.
结论:
- 这一系统性审查将提供证据,证明数字通信在改善PrEP遵守方面的有效性.
- 调查结果将为风险人群中预防艾滋病毒的策略提供信息.
- 该研究旨在提供有关利用数字工具实现更好的公共卫生结果的见解.
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