连续流动左心室辅助器件患者的假体的命运
Daisuke Kaneyuki1, Krushang Patel1, Alice V Vinogradsky1
1From the Division of Cardiac, Thoracic & Vascular Surgery, Department of Surgery, Columbia University Irving Medical Center, New York-Presbyterian Hospital, New York, New York.
概括
在使用左心室辅助器件 (LVAD) 的患者中,假体门并发症并不常见. 然而,大动脉生物假肢功能障碍可能发生在LVAD植入后的一年内.
科学领域:
- 心脏病学 心脏病学
- 心血管外科心血管外科
- 生物医学工程 生物医学工程
背景情况:
- 左心室辅助器件 (LVAD) 对于末期心力衰竭管理至关重要.
- 假体门和LVAD之间的相互作用需要进一步调查患者的治疗结果.
研究的目的:
- 评估LVAD接受者与假肢相关的发病率和死亡率的发生率和特征.
- 评估 LVAD 患者假体门的长期性能.
主要方法:
- 在2004年4月至2022年12月期间接受HeartMate II或3 LVAD的726名患者的回顾性评估.
- 包括患有任何假的患者,分析置换时间 (LVAD前,后或后).
- 评估门位置 (大动脉,额头,三) 和类型 (机械与生物假体).
主要成果:
- 74名患者 (10.2%) 在LVAD插入周围进行了门置换.
- 一个与门相关的死亡是由于严重的大动脉生物假体缺陷而发生的.
- 17.9%的有大动脉生物假体的患者在心声学上表现出功能障碍,LVAD后1年的中位时间到功能障碍.
结论:
- 在LVAD患者中,与假肢相关的死亡率和重新干预率很低.
- 大动脉生物假体门功能障碍是一种潜在的并发症,通常在LVAD植入后的第一年内发展.
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