在阿联的类风湿性关节炎患者中共发病率:一个病例控制研究
Jamal Al-Saleh1, Naureen Ali Khan2, Noura Zamani2
1Department of Rheumatology, Dubai Academic Health Corporation, Dubai, UAE drjamalalsaleh@hotmail.com.
BMJ open
|November 12, 2024
概括
与对照组相比,迪拜的类风湿性关节炎 (RA) 患者患病率更高,包括心脏病和骨质疏松症. 在RA患者中,肥胖进一步增加了并发症的发生率.
科学领域:
- 类风湿病学 类风湿病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 关于阿拉伯患者患有类风湿性关节炎 (RA) 的并发症患病率的数据有限.
- 将国际共发病率数据推断到当地人口是具有挑战性的.
- 了解当地的并发病模式对于有效的患者管理至关重要.
研究的目的:
- 为了确定阿联国民RA患者的并发症的患病率.
- 为了比较RA患者和匹配的对照组之间的并发症率.
- 为了研究身体质量指数 (BMI) 与RA患者的并发症之间的关联.
主要方法:
- 追溯的,案例控制研究设计.
- 包括439名RA患者和1756名来自迪拜医疗机构的年龄和性别匹配的对照.
- 从电子医疗记录中提取人口统计和并发症的数据.
主要成果:
- 42.8%的RA患者至少有一种并发症,对照组为36.2% (OR1.3,p<0.01).
- 关节炎患者的缺血性心脏病 (OR 3.9),纤维肌痛 (OR 25),白内障 (OR 5.8),骨质疏松症 (OR 6.8) 和膝关节骨关节炎 (OR 6.1) 发生率显著更高.
- 与非肥胖的RA患者相比,肥胖的RA患者表现出更高的并发症发病率.
结论:
- 在这个阿联队伍中,RA患者患心血管,肺和肌肉骨并发症的可能性更高.
- 肥胖与RA患者的并发症负担增加有关.
- 这些发现凸显了在该人群中治疗RA时需要进行全面的并发症查的必要性.
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