诺瓦体积流速与TOF信号强度比率之间的相关性:单边内动脉封闭的值
Fabian Wolf1, Elisa Colombo2, Tilman Schubert3
1Department of Neurosurgery and Clinical Neuroscience Center, Universität Zürich, Universitätsspital Zürich, Frauenklinikstrasse 10, 8091, Zurich, ZH, Switzerland.
飞行时间信号强度比 (SIR) 与非侵入性最佳血管分析和定量磁共振血管学 (NOVA-QMRA) 在内动脉 (ICA) 阻塞中的流量相关. 这一发现有助于评估中风患者的大脑血液动力学和附带担保.
科学领域:
- 神经成像是一种神经成像.
- 脑血管疾病是脑血管疾病.
- 医学物理 医学物理
背景情况:
- 内动脉样硬化疾病 (ICAD) 影响大脑血液动力学.
- 非侵入性最佳血管分析定量磁共振血管造影 (NOVA-QMRA) 是评估ICAD的一个关键工具.
- 飞行时间 (TOF) MRA 是常用的,但它的定量流量评估是有限的.
研究的目的:
- 调查NOVA-QMRA推导的体积流速 (VFR) 和TOF MRA信号强度比 (SIR) 之间的相关性.
- 分析这些参数在M1和P2段双边在单边内动脉 (ICA) 封闭的患者.
- 评估TOF SIR在ICAD中对定性流量评估的实用性.
主要方法:
- 55名患有单边ICA闭塞的患者进行了回顾性分析,接受了NOVA-QMRA.
- 在双边M1和P2段使用NOVA-QMRA和TOF SIR测量VFR.
- 用皮尔森相关性和韦尔奇t测试来分析数据.
主要成果:
- 在ipsilateral和contralateral两部分 (分别r=0.536和r=0.757) 中发现了TOF SIR和NOVA VFR之间的显著相关性.
- 较高的VFR和TOF SIR被观察到与ipsilateral相比,相反的M1细分市场.
- 在P2段中观察到相反的模式,这表明潜在的勒普托门关节担保.
结论:
- TOF SIR与相对比衍生的流量体积在症状ICA封闭中显著相关,无论中风阶段如何.
- 在ipsilateral P2段中的高VFR和TOF SIR可能表明leptomeningeal担保.
- 标准TOF MRA可以帮助定性流量评估,而NOVA-QMRA则提供精确的定量测量.
更多相关视频
06:39Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice
Published on: April 13, 2015
10:41Analysis of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage with High Frequency Transcranial Duplex Ultrasound
Published on: June 3, 2021
相关概念视频
Blood Flow
Cardiac Output and Stroke Volume
In an average resting adult male, the typical cardiac output averages...
Regulation of Stroke Volume
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
Autoregulation of Blood Flow
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation.
Cardiac Output II: Effect of Stroke Volume on Cardiac Output
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
Pipe Flowrate Measurement: Problem Solving
