斑点海 (Phoca largha) 肠道微生物群中的不稳定的病原体概况和与息地微生物群的有限周转
Jing Du1, Zhen Wang1, Xianggang Gao1
1Dalian Key Laboratory of Conservation Biology for Endangered Marine Mammals, Liaoning Ocean and Fisheries Science Research Institute, Dalian, 116023, Liaoning, China.
概括
监测斑点海 (Phoca largha) 的肠道微生物群对于海洋哺乳动物的健康至关重要. 它们的肠道微生物群较少多样化,与它们的息地不同,在一些野生个体中存在潜在的疾病风险.
科学领域:
- 海洋哺乳动物健康
- 微生物组研究 微生物组研究
- 生态生态学 生态生态学
背景情况:
- 像斑点海 (Phoca largha) 这样的哨兵物种是海洋生态系统健康的关键指标.
- 了解肠道微生物群及其与环境的相互作用对于评估海洋哺乳动物福祉至关重要.
研究的目的:
- 为了分析捕获和野生种群中斑点海 (Phoca largha) 的肠道微生物组成.
- 为了比较斑点海的肠道微生物组与它们周围的息地微生物组.
- 为了确定潜在的病原体概况,并评估斑点海的疾病风险.
主要方法:
- 使用PacBio技术进行全长细菌16S rRNA基因测序.
- 捕养和野生斑点海的便样本的分析.
- 与息地微生物群样本进行比较.
- 病原体鉴定,多样性分析和网络分析.
- 源 追踪器分析用于微生物营业额估计.
主要成果:
- 野生和养的斑点海的肠道微生物群表现出类似的病原体丰富性和丰富性,野生海的变异性更高.
- 斑点海肠道微生物群的多样性明显低于它们的息地微生物群.
- 坚果菌在斑点海肠道微生物群中占主导地位,而蛋白质菌在它们的息地中普遍存在.
- 网络分析表明,斑点海的肠道微生物结构简单而薄弱.
- 在海肠和息地微生物之间微生物的交换率很低 (<0.1%).
结论:
- 提供了斑点海 (Phoca largha) 病原体概况的基线数据.
- 突出了斑点海肠道微生物群和息地微生物群之间的显著差异.
- 表明斑点海和它们的直接环境之间有限的直接微生物交换.
- 由于肠道微生物群的变化,这表明野生斑点海的一个子集存在潜在的疾病风险.
更多相关视频
09:49Prospecting Microbial Strains for Bioremediation and Probiotics Development for Metaorganism Research and Preservation
Published on: October 31, 2019
22.2K
09:44Characterization of a Pathogenic Escherichia coli Strain Derived from Oreochromis spp. Farms Using Whole-Genome Sequencing
Published on: December 23, 2022
2.1K
相关概念视频
01:30Marine Microbial Ecology
Marine microbial ecosystems are shaped by distinct physicochemical limits, including high salinity, low nutrient availability, and fluctuating oxygen levels. These conditions favor smaller microbial cell sizes, which maximize their surface-to-volume ratio for efficient nutrient uptake.Microbial activity and community composition are closely linked to biogeochemical cycles, particularly in dynamic environments like estuaries, where halotolerant microbes thrive in response to variable salinity...
01:18Deep Sea Microbial Ecology
The deep ocean and its underlying sediments represent vast, largely unexplored microbial habitats that extend far beyond the sunlit photic zone. The photic (euphotic) zone typically spans the upper ~100–200 meters of pelagic waters in the open ocean, but its depth varies geographically and seasonally, where sufficient light supports photosynthetic life. Below this lies the deep sea, spanning roughly 1000–6000 meters (bathypelagic to abyssal zones), with deeper hadal trenches extending beyond...
01:22Introduction to the Human Microbiota
Microorganisms colonize various regions of the human body, including the mouth, nasal passages, throat, stomach, intestines, urogenital tract, and skin. The total number of microbial cells is estimated to range from 10¹³ to 10¹⁴—comparable to, or exceeding, the number of human somatic cells. This host–microbiome relationship has led to the conceptualization of humans as supraorganisms, wherein microbial communities perform vital roles in development, immunity, and disease...
01:27Microbiota of the Stomach and Small Intestine
The human gastrointestinal (GI) tract is characterized by distinct physicochemical conditions that shape its microbial communities. Among these, the stomach presents a particularly challenging environment for microbial colonization due to its highly acidic pH, ranging from 1 to 3. This extreme acidity effectively limits microbial density. However, certain acid-tolerant microorganisms are capable of surviving in this niche. Notably, Helicobacter pylori can colonize the gastric mucosa,...
01:27Microbiota of the Large Intestine
The large intestine hosts the most densely populated microbial ecosystem in the human body. This complex community primarily consists of anaerobic bacteria, with Bacillota (formerly Firmicutes) and Bacteroidota (formerly Bacteroidetes) as the predominant groups. The distribution of these microbes varies along different sections of the large intestine, influenced by local environmental factors such as oxygen availability and nutrient composition.The cecum, located at the beginning of the large...
01:18Dysbiosis of the Gut Microbiota
The human gut microbiome includes a diverse array of microbial species, including beneficial commensals and opportunistic pathogens, which interact to support host health. These microbes contribute to essential functions such as nutrient metabolism, immune system modulation, and maintenance of intestinal barrier integrity. However, disruptions to this equilibrium—referred to as dysbiosis—can have widespread physiological consequences.Dysbiosis is often characterized by reduced microbial...