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Updated: Jun 7, 2025

Efficient iPS Cell Generation from Blood Using Episomes and HDAC Inhibitors
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Efficient iPS Cell Generation from Blood Using Episomes and HDAC Inhibitors

Published on: October 28, 2014

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由Ldh调节的Hdac1的乳化阻止了多能转化为2C的状态转换

Qiman Dong1, Xiaoqiong Yang1, Lingling Wang1

  • 1Institute of Translational Medicine, Tianjin Union Medical Center, State Key Laboratory of Medicinal Chemical Biology, Tianjin Key Laboratory of Protein Sciences, Frontiers Science Center for Cell Responses, National Demonstration Center for Experimental Biology Education and College of Life Sciences, Nankai University, Tianjin, 300071, China.

Stem cell research & therapy
|November 13, 2024
PubMed
概括

细胞代谢通过蛋白质乳糖化调节胚胎干细胞 (ESC) 的多能性. 乳酸化Hdac1沉默2C基因,将新陈代谢与多能状态过渡联系起来.

关键词:
类似双细胞细胞的细胞.胚胎干细胞是一种胚胎干细胞.H3K27ac 在线阅读在 Hdac1 的情况下.乳化 乳化 乳化

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A Two-Step Strategy that Combines Epigenetic Modification and Biomechanical Cues to Generate Mammalian Pluripotent Cells08:01

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