跨腹腔超声波用于诊断儿童功能性便秘的价值:系统性审查和元分析
Duc Long Tran1,2, Phu Nguyen Trong Tran1,2, Paweena Susantitaphong3,4
1Clinical Sciences Program, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Clinical and experimental pediatrics
|November 13, 2024
概括
跨腹部超声波可以有效地诊断儿童功能性便秘 (FC). 超过31毫米的直肠直径 (RD) 显示出良好的准确性,使超声波成为检测FC的宝贵工具.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 诊断成像 诊断成像 诊断成像
- 医学超声波 医学超声波
背景情况:
- 功能性便秘 (FC) 是一个常见的儿科疾病.
- 腹腔超声波正在成为FC的非侵入性诊断工具.
- 使用超声波扫描进行FC的准确诊断参数需要进一步评估.
研究的目的:
- 系统地审查和元分析儿童功能性便秘的腹腔超声波诊断的诊断准确性.
- 评估关键参数,如直肠直径 (RD) 和前直肠壁厚度.
- 在诊断FC时确定RD的最佳切割值.
主要方法:
- 在主要医疗数据库 (Ovid MEDLINE,Embase,Scopus,PubMed) 进行系统搜索,截至2023年9月29日.
- 包括14项涉及1255名儿童的研究,比较了患有和没有FC的儿童的超声波参数.
- 使用随机效应模型进行元分析,以计算加权平均差异和诊断性能指标 (灵敏度,特异性,AUC).
主要成果:
- 与对照组相比,患有FC的儿童的平均直肠直径 (RD) 显著增加 (MD:10.35 mm,P<0.001).
- 31毫米的最佳RD切线显示出良好的诊断准确性 (AUC:0.86,灵敏度:0.75,特异性:0.84).
- 在有便秘和没有便秘的儿童之间,在前直肠壁厚度上没有发现统计学上显著的差异.
结论:
- 腹腔超声波,特别是测量直肠直径 (RD),是诊断儿科功能性便秘的宝贵工具.
- 31毫米的RD切线为儿童的FC提供了良好的诊断准确性.
- 进一步的研究可能会探索前直肠壁厚度的作用,尽管它在本次元分析中没有显著意义.
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