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Updated: Jul 27, 2026

Single-step Purification of Macromolecular Complexes Using RNA Attached to Biotin and a Photo-cleavable Linker
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关联mRNA的简洁的亲和基净化用于结构-活动关系研究核糖修饰模式的研究

Hiroki Yamada1, Hiroto Iwai1, Fumitaka Hashiya2

  • 1Modality Research Laboratories 1, Research Unit, Research Division, Kyowa Kirin Co., Ltd., 3-6-6 Asahi, Machida, Tokyo, 194-8533, Japan.

Chembiochem : a European journal of chemical biology
|November 13, 2024
PubMed
概括

化学合成的信使RNA (mRNA) 修改增强了稳定性和翻译性. 一种新的两步亲和力净化方法快速分离修改的mRNA用于制药应用.

关键词:
关联性净化净化方法修饰核酸的改性核酸是一种核酸是核酸中的一种.这是一个RNARNARNARNARNA.关节的绑定 关节的绑定

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相关概念视频

Tagging and Fusion Proteins01:24

Tagging and Fusion Proteins

Proteins are involved in several cellular processes and biochemical reactions. Analyzing a specific protein of interest requires it to be isolated from the other proteins in the cell. This is achieved by overexpressing the specific gene in a suitable host to produce large quantities of the target protein. A tag or label is recombined with the gene to produce a fusion protein containing the target protein and the tag. The tags on these fusion proteins can then be used for easy detection and...