了解唐氏综合征神经病变发生的观点和研究趋势:一本书法分析分析
Tan Huang1, Xin-Jieh Lam2, Chong-Teik Lim1
1Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Malaysia.
Journal of intellectual disabilities : JOID
|November 13, 2024
概括
这项对唐氏综合征 (DS) 和阿尔茨海默病 (AD) 研究的文献分析揭示了关键趋势和贡献者. 与阿尔茨海默氏症相关的基因显著影响DS神经病变发生,指导未来的研究和护理.
科学领域:
- 神经科学是一个神经科学.
- 遗传学 遗传学 是一个
- 图书统计学 图书统计学
背景情况:
- 唐氏综合征 (DS) 与认知障碍和阿尔茨海默病 (AD) 类似症状的高患病率有关.
- 了解DS的神经病变发生是开发有效干预措施的关键.
- 图书统计分析提供了研究趋势和合作的定量概述.
研究的目的:
- 对有关唐氏综合征及其神经病变发生的研究进行全面的文献分析.
- 确定该领域的关键趋势,有影响力的贡献者和新兴研究领域.
- 阐明与阿尔茨海默氏症相关的基因和蛋白质在DS神经病理学中的作用.
主要方法:
- 从科学网络核心集合 (2000-2023) 中对5,082篇论文进行了图书统计分析.
- 使用VOSviewer,CiteSpace和R包"bibliometrix"进行数据分析.
- 分析了共同作者,共同引用,共同发生,合作网络,引用和关键词爆发.
主要成果:
- 美国在这一领域的研究成果和引用率处于领先地位.
- 关键的研究领域包括阿尔茨海默病,神经发育,炎症和神经发生.
- 与阿尔茨海默氏症相关的基因和蛋白质在一生中始终与DS神经病理过程有关.
结论:
- 这项长达22年的图书统计调查突出了唐氏综合征神经病变发生研究中的重要趋势和焦点.
- 与阿尔茨海默氏症相关因素的普遍作用强调了它们在DS中的重要性.
- 这些发现为推进研究和对唐氏综合征患者的临床护理提供了基础知识.
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