盆腔辐射后的泌尿生殖系统毒性:复杂泌尿学表现的前性审查
Rowan V David1,2, Asif Islam1, John Miller1
1Department of Urology, Lyell McEwin Hospital, Elizabeth Vale, Adelaide, Australia.
Asian journal of urology
|November 13, 2024
概括
盆腔放射治疗后的晚期生殖尿道并发症是常见的和严重的,显著影响泌尿病学工作量. 这些问题通常在治疗后5年出现,需要大量的医疗干预.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 辐射瘤学 辐射瘤学
- 在瘤学瘤学.
背景情况:
- 最近的试验低估了盆腔放射治疗后的晚期生殖尿道 (GU) 并发症.
- 晚期GU并发症可以在治疗后5年内表现出来.
研究的目的:
- 为了确定一个机构的骨盆放射治疗后晚期GU并发症的负担.
- 分析患者的人口统计,放射治疗细节和晚期GU毒性的管理因素.
主要方法:
- 在盆腔放射治疗后 (2018年11月至2019年11月) 对GU并发症呈现的前性研究.
- 对于晚期毒性前列腺癌 (PCa) 患者的子组分析.
- 评估患者的人口统计,放射治疗,并发症和管理.
主要成果:
- 46名患者有117次接触;56.4%的人重复接触.
- 前列腺癌患者 (84.8%) 主要受到辐射诱导的出血性囊炎的影响.
- 显著的手术 (42.7%) 和非手术 (32.0%) 管理;9名患者需要输血.
结论:
- 由于晚期盆腔辐射毒性,选择性和紧急泌尿病学工作负担很大.
- 晚期GU毒性 (放射治疗后≥5年) 是常见的和严重的.
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