Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Linear Approximation in Time Domain01:21

Linear Approximation in Time Domain

64
Nonlinear systems often require sophisticated approaches for accurate modeling and analysis, with state-space representation being particularly effective. This method is especially useful for systems where variables and parameters vary with time or operating conditions, such as in a simple pendulum or a translational mechanical system with nonlinear springs.
For a simple pendulum with a mass evenly distributed along its length and the center of mass located at half the pendulum's length,...
64
BIBO stability of continuous and discrete -time systems01:24

BIBO stability of continuous and discrete -time systems

348
System stability is a fundamental concept in signal processing, often assessed using convolution. For a system to be considered bounded-input bounded-output (BIBO) stable, any bounded input signal must produce a bounded output signal. A bounded input signal is one where the modulus does not exceed a certain constant at any point in time.
To determine the BIBO stability, the convolution integral is utilized when a bounded continuous-time input is applied to a Linear Time-Invariant (LTI) system....
348
Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving01:29

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving

42
Mechanistic models play a crucial role in algorithms for numerical problem-solving, particularly in nonlinear mixed effects modeling (NMEM). These models aim to minimize specific objective functions by evaluating various parameter estimates, leading to the development of systematic algorithms. In some cases, linearization techniques approximate the model using linear equations.
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
42
Linear time-invariant Systems01:23

Linear time-invariant Systems

216
A system is linear if it displays the characteristics of homogeneity and additivity, together termed the superposition property. This principle is fundamental in all linear systems. Linear time-invariant (LTI) systems include systems with linear elements and constant parameters.
The input-output behavior of an LTI system can be fully defined by its response to an impulsive excitation at its input. Once this impulse response is known, the system's reaction to any other input can be...
216
Feedback control systems01:26

Feedback control systems

288
Feedback control systems are categorized in various ways based on their design, analysis, and signal types.
Linear feedback systems are theoretical models that simplify analysis and design. These systems operate under the principle that their output is directly proportional to their input within certain ranges. For instance, an amplifier in a control system behaves linearly as long as the input signal remains within a specific range. However, most physical systems exhibit inherent nonlinearity...
288
State Space Representation01:27

State Space Representation

165
The frequency-domain technique, commonly used in analyzing and designing feedback control systems, is effective for linear, time-invariant systems. However, it falls short when dealing with nonlinear, time-varying, and multiple-input multiple-output systems. The time-domain or state-space approach addresses these limitations by utilizing state variables to construct simultaneous, first-order differential equations, known as state equations, for an nth-order system.
Consider an RLC circuit, a...
165

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Beyond Endoscopy: A Narrative Review of the Emerging Role of Gastroenterologists in Obesity Medicine, GLP-1 (Glucagon-Like Peptide-1) Therapy, and Metabolic Care.

Cureus·2026
Same author

Predicting Inflammatory Bowel Disease Flares Using Artificial Intelligence and Remote Monitoring: Toward Proactive Disease Management.

Cureus·2026
Same author

Recovering Reward Functions From Distributed Expert Demonstrations via Bi-Level Maximum-Likelihood Optimization.

IEEE transactions on neural networks and learning systems·2026
Same author

Long-Term Endoscopic Management of Recurrent High-Grade Dysplasia and Intramucosal Carcinoma in an Inoperable Barrett Patient.

ACG case reports journal·2026
Same author

National Mortality Patterns of Cancer Cachexia in Gastrointestinal Malignancies in the United States: A Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research (CDC WONDER) Analysis (2018-2023).

Cureus·2026
Same author

The crossroads between osteosarcopenia and intrinsic capacity-a narrative review.

The journals of gerontology. Series A, Biological sciences and medical sciences·2026
Same journal

An Extended Generalized Prandtl-Ishlinskii Hysteresis Model for I<sup>2</sup>RIS Robot.

IFAC-PapersOnLine·2026
Same journal

Learning Approximate Symbolic Solutions to Burgers' Equation using Symbolic Regression.

IFAC-PapersOnLine·2025
Same journal

Efficient Least-Squares State Estimation Using Uniform Sampling.

IFAC-PapersOnLine·2025
Same journal

Identifying the dynamics of interacting objects with applications to scene understanding and video temporal manipulation.

IFAC-PapersOnLine·2025
Same journal

Identification of Low Order Systems in a Loewner Framework.

IFAC-PapersOnLine·2025
Same journal

Rational Maps for System Identification.

IFAC-PapersOnLine·2025
查看所有相关文章

相关实验视频

Updated: Jun 7, 2025

A Protocol for Real-time 3D Single Particle Tracking
10:16

A Protocol for Real-time 3D Single Particle Tracking

Published on: January 3, 2018

14.8K

基于内核的粒子过用于在部分观察到的布尔动态系统中进行可扩展的推理.

Mohammad Alali1, Mahdi Imani1

  • 1Northeastern University, Department of Electrical and Computer Engineering, Boston, MA, USA.

IFAC-PapersOnLine
|November 13, 2024
PubMed
概括
此摘要是机器生成的。

本研究介绍了一种基于核的新型粒子过方法,用于在部分观察到的布尔动态系统 (POBDS) 中有效推断参数. 这种方法提高了复杂的生物和安全网络的可扩展性.

关键词:
贝叶斯式优化 贝叶斯式优化生物网络 生物网络推理推理是指一个推理.部分观察到的布尔动态系统颗粒过器的使用方法

更多相关视频

Image-based Lagrangian Particle Tracking in Bed-load Experiments
10:32

Image-based Lagrangian Particle Tracking in Bed-load Experiments

Published on: July 20, 2017

8.9K
Simultaneous Measurement of Turbulence and Particle Kinematics Using Flow Imaging Techniques
10:53

Simultaneous Measurement of Turbulence and Particle Kinematics Using Flow Imaging Techniques

Published on: March 12, 2019

7.0K

相关实验视频

Last Updated: Jun 7, 2025

A Protocol for Real-time 3D Single Particle Tracking
10:16

A Protocol for Real-time 3D Single Particle Tracking

Published on: January 3, 2018

14.8K
Image-based Lagrangian Particle Tracking in Bed-load Experiments
10:32

Image-based Lagrangian Particle Tracking in Bed-load Experiments

Published on: July 20, 2017

8.9K
Simultaneous Measurement of Turbulence and Particle Kinematics Using Flow Imaging Techniques
10:53

Simultaneous Measurement of Turbulence and Particle Kinematics Using Flow Imaging Techniques

Published on: March 12, 2019

7.0K

科学领域:

  • 系统生物学 系统生物学
  • 计算生物学 计算生物学
  • 网络安全 网络安全

背景情况:

  • 部分观察布尔动态系统 (POBDS) 对于建模基因动态和网络安全非常有效.
  • 由于计算成本高,POBDS的现有推断方法面临可扩展性问题.
  • 有效的参数推断对于理解复杂的生物和安全系统至关重要.

研究的目的:

  • 为部分观察布尔动态系统 (POBDS) 开发一种可扩展的推理方法.
  • 为解决POBDS的概率评估和参数空间探索中的计算挑战.
  • 使用POBDS提高复杂生物和安全网络建模的效率.

主要方法:

  • 建议采用基于内核的颗粒过方法.
  • 用高斯过程 (GPs) 高效地近似概率函数.
  • 贝叶斯优化用于指导参数搜索,平衡探索和利用.

主要成果:

  • 拟议的方法显著提高了POBDS推断的可扩展性.
  • 高斯过程有效地代表了不确定的概率评估.
  • 贝叶斯优化有效地识别最佳参数,减少计算负担.

结论:

  • 基于内核的粒子过方法为POBDS推断提供了一个可扩展的解决方案.
  • 这种方法提高了POBDS在系统生物学和网络安全中的应用性.
  • 该方法在哺乳动物细胞周期和T细胞白血病网络上成功验证.