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无增强CT作为对比增强CT的替代品,用于评估脏冷凝区
Hiroki Yano1, Hiroki Higashihara2, Yasushi Kimura2
1Department of Diagnostic and Interventional Radiology, Osaka University Graduate School of Medicine, Suita, JPN.
Cureus
|November 13, 2024
概括
无增强CT (UE-CT) 可以有效评估细胞癌 (RCC) 患者的冷缩区,为患有功能障碍的人提供对比增强CT (CE-CT) 的可行替代方案. 该方法显示可靠的相关性与CE-CT用于评估治疗成功.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
背景情况:
- 增加细胞癌 (RCC) 检测需要有效的微创治疗,如冷.
- 增强对比度CT (CE-CT) 是冷后评估的标准,但功能障碍在许多患者中限制了对比剂的使用.
- 非增强型CT (UE-CT) 提供了一个潜在的替代方案,用于评估患有功能障碍的患者的冷化区域.
研究的目的:
- 评估UE-CT在评估细胞癌 (RCC) 患者的冷化区域中的有效性.
- 为了比较UE-CT与CE-CT的诊断性能,用于冷后的随访.
- 确定UE-CT是否可以在患有功能障碍的患者中作为CE-CT的可靠替代品.
主要方法:
- 54名患者 (58种瘤) 进行CT导向冷化后期分析.
- 早期随访CT扫描 (在三天内) 包括UE-CT和CE-CT.
- 在UE-CT和CE-CT测量CT衰减值和瘤体积以进行比较.
主要成果:
- UE-CT在冷剥离区显示出高衰减,而CE-CT显示出低衰减.
- 在UE-CT和CE-CT中,在正常脏和冷移除区域之间观察到显著的衰减值差异.
- 在CE-CT上未增强区域的中位体积和UE-CT上的减弱变化没有显著差异,并且显示出强烈的相关性 (r = 0.95).
结论:
- UE-CT可靠地估计了RCC患者冷后的除区域,与CE-CT发现有很好的相关性.
- 尽管对比度较低,但在UE-CT上可以检测到除区域,这使其成为无法接受对比剂的患者的宝贵工具.
- 建议与更大的队列进行进一步的研究,以验证UE-CT的临床实用性和可重复性,以进行冷后评估.
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