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孕产妇肥胖对孕产妇和带血样本中氧化参数的影响

Gamze Gok¹, Ceylan Bal², Raziye Desdicioglu³

¹Medical Biochemistry, Ankara Bilkent City Hospital, Ankara, TUR.

|November 13, 2024

概括

孕产妇肥胖与母亲和新生儿的氧化应激增加有关. 这凸显了体重管理对健康怀孕和胎儿福祉的重要性.

科学领域:

产科和妇科产科和妇科
生物化学生物化学
围产儿医学围产儿医学

背景情况:

氧化应激与各种妊娠并发症有关.
孕产妇的肥胖在妊娠期间带来了独特的生理挑战.
了解肥胖中的氧化应激标志物对于围产期健康至关重要.

研究的目的:

为了研究和比较母体和带血中的氧化应激参数.
为了评估肥胖和不肥胖的孕妇之间的差异.
为了确定受孕妇肥胖影响的特定氧化应激标志物.

主要方法:

分析了30名肥胖和35名不肥胖的孕妇 (18-40岁) 的母体和带血样本.
测量二醇/二硫化物平衡 (原生二醇,总二醇,二硫化物),白蛋白,缺血变异性白蛋白 (IMA),骨髓氧化酶 (MPO),催化酶,血红和细胞内谷氨.
肥胖和非肥胖群体之间的氧化应激参数的统计比较.

主要成果:

肥胖的母亲在母亲的血液中表现出显著更高的二硫化物,甲酶和血红的水平.
肥胖母亲的子女的带血显示出明显升高的二硫化物,IMA和催化酶水平.
在非肥胖母亲的后代的带血中,白蛋白水平显著更高.

结论:

孕产妇肥胖与母亲和新生儿的氧化应激增加密切相关.
增加的氧化压力可能会导致不利的孕产妇和胎儿后果.
在生育年龄期间控制体重对于优化母亲和胎儿健康结果至关重要.

关键词:

带状血是指带状血中的部分.母亲的血液来自母亲的血液.肥胖肥胖肥胖肥胖肥胖肥胖肥胖肥胖氧化应激是一种氧化应激.怀孕怀孕怀孕怀孕怀孕

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