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在NIR-II地区,用于多功能生物医学成像的多功能光体的最新进展
Kaiming Ma1, Qunying Jiang1, Yang Yang1
1College of Energy Materials and Chemistry, Inner Mongolia University, Hohhot 010021, China. jiangqy@imu.edu.cn.
Journal of materials chemistry. B
|November 13, 2024
概括
第二次近红外 (NIR-II) 光成像提供了高分辨率的深层组织可视化. 本综述详细介绍了NIR-II探针,它们的应用以及未来临床翻译的挑战.
科学领域:
- 生物医学光学 生物医学光学
- 医疗成像医学成像
- 纳米技术 纳米技术
背景情况:
- 在第二近红外 (NIR-II) 区域 (1000-1700 nm) 的光成像提供了卓越的深层组织可视化.
- 这是由于生物组织中光吸收,散射和自光的减少.
- 众多的NIR-II光探头已被开发用于各种应用.
研究的目的:
- 审查NIR-II光成像的优势.
- 系统地讨论NIR-II光探针的分类,设计和优化.
- 突出这些探针的生物医学应用,并讨论未来的临床翻译.
主要方法:
- 对NIR-II光成像和探针现有研究的文献综述.
- 对NIR-II光探针设计策略的系统分类和分析.
- 讨论体内应用和临床翻译的挑战.
主要成果:
- 与传统方法相比,NIR-II光成像提供了更好的分辨率和深度透.
- 已经开发出了各种各样的NIR-II光探头,具有多种功能.
- 在体内应用方面取得了重大进展,尽管临床翻译面临障碍.
结论:
- NIR-II光成像是一种强大的工具,用于深层组织可视化和生物医学研究.
- 继续开发新型NIR-II探针对于推进体内成像至关重要.
- 克服探头设计和成像系统的挑战是临床转化的关键.
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