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分子动力学模拟提供了ULK-101的强度和对自激酶ULK1/2的选择性的洞察力

Robert M Vaughan1, Bradley M Dickson2, Katie R Martin1

  • 1Pediatrics and Human Development, College of Human Medicine, Michigan State University, Grand Rapids, MI, USA.

Journal of biomolecular structure & dynamics
|November 13, 2024
PubMed
概括

分子动力学模拟揭示了ULK-101如何与ULK2激酶域结合. 这种理解有助于开发新的癌症疗法,向与自相关的激酶.

关键词:
在ULK-101中,ULK1 是一个ULK1ULK2 ULK2 ULK2 ULK2 ULK2 ULK2 ULK2 ULK2 ULK2适应性偏见是适应性的偏见.自自是自的过程.激酶激酶的作用是什么分子动力学模拟,分子动力学模拟小分子抑制剂小分子抑制剂

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