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Updated: Jun 7, 2025

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
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Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production

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树突细胞中的I型干扰素信号限制了直接抗原呈现和CD8+T细胞对关节性阿尔法病毒的反应

Christopher B Bullock1,2, Leran Wang1, Brian C Ware3

  • 1Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.

mBio
|November 13, 2024
PubMed
概括

罗斯河病毒 (RRV) 感染会损害CD8+T细胞的反应,导致慢性疾病. 阻断树突细胞中的I型干扰素信号增强T细胞激活和病毒清除,这表明阿尔法病毒感染的新治疗点.

关键词:
在T细胞,T细胞.T细胞免疫力免疫力艾尔法病毒 (alphavirus) 是一种干扰子干扰子干扰子病毒病原体的病毒病原体.

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High-throughput Quantitative Real-time RT-PCR Assay for Determining Expression Profiles of Types I and III Interferon Subtypes10:00

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