葡萄牙十年的止痛药使用模式和经济影响
Nuno Duarte1, João Paulo Martins2,3, Jose-Ángel García-Pedraza4,5
1REQUIMTE/LAQV, Escola Superior de Saúde, Instituto Politécnico do Porto, Rua Dr. António Bernardino de Almeida, Porto, Portugal.
British journal of clinical pharmacology
|November 13, 2024
概括
2012年至2022年间,葡萄牙的阿片类药物和辅助剂使用显著增加,葡萄牙在2022年比西班牙和丹麦的阿片类药物消费量更低. 管理成本需要仿制药和市场监测.
科学领域:
- 药物经济学 药物经济学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 分析止痛药,辅助药和阿片类药物消费趋势对于了解医疗保健资源配置至关重要.
- 葡萄牙的10年数据 (2012-2022) 为国家药物使用模式提供了有价值的案例研究.
研究的目的:
- 评估葡萄牙10年的止痛药,辅助药和阿片类药物的消费和经济模式.
- 将葡萄牙2022年消费模式与西班牙和丹麦的消费模式进行比较.
主要方法:
- 葡萄牙国家药品和健康产品管理局的销售和国家卫生服务 (NHS) 成本数据.
- 将销售数据转换为每天1000名居民的定义每日剂量 (DDD),使用解剖治疗化学 (ATC) 分类.
- 在葡萄牙,西班牙和丹麦之间进行比较分析时使用了千平方测试.
主要成果:
- 经典止痛药的使用保持稳定;伊布罗芬是最常被消耗的.
- gabapentinoid (辅助剂) 的使用增加了84%,主要是由pregabalin推动的.
- 弱性阿片类药物 (特拉马多尔) 的使用增加了117%,强性阿片类药物 (塔达尔) 的使用增加了618%.
- 与丹麦和西班牙相比,2022年葡萄牙的阿片类药物消费总量最低.
- 国家卫生服务系统 (NHS) 对止痛药的支出增加,主要是由于阿片类药物,但相对支出保持稳定.
结论:
- 葡萄牙的阿片类药物处方量显著增加,反映了西班牙和丹麦的趋势.
- 通用药的开发和警的市场监测对于管理与阿片类药物消费增加相关的成本至关重要.
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