马匹听力斑块中的临床和流行病学方面
Gabryele Gomidy Rodrigues1, Dara Santos Alves1, Cristiana Raach Bromberger2
1School of Veterinary Medicine, Universidade Federal de Uberlândia, Av. Mato Grosso n. 3289 - Bloco 2S. Bairro Umuarama. CEP 38405-314, Uberlândia, Minas Gerais, Brazil.
Veterinary research communications
|November 13, 2024
概括
在巴西的Mangalarga Marchador (MM) 和Quarter Horse (QH) 品种中,耳斑很常见,MM马的患病率更高. 马匹瘤病毒 (EcPV),特别是 EcPV4,在这些病变中经常被检测到.
科学领域:
- 兽医皮肤病学 兽医皮肤病学
- 马群病毒学 马群病毒学
- 流行病学 流行病学
背景情况:
- 马的听力斑与马匹瘤病毒 (EcPV) 有关,但品种特定的流行率和风险因素尚未得到充分了解.
- 了解这些关联对于马群的有效管理和预防策略至关重要.
研究的目的:
- 确定在巴西的Mangalarga Marchador (MM) 和四分之一马 (QH) 品种中听力斑块的临床患病率.
- 为了调查听力斑块与各种风险因素之间的联系.
- 在听力斑块活检中检测出 EcPV DNA 的存在和类型.
主要方法:
- 临床评估400MM和425QH马的听力斑块.
- 收集有关品种,性别,年龄,病变特征,外寄生虫,管理,耳朵剪切和触摸敏感性的数据.
- 从30匹马的活检进行PCR分析,以确定ecpvDNA类型 (1-10).
主要成果:
- 在41.5%的MM马和33.6%的QH马中发现了听觉斑块,MM马的患病率显著更高.
- 在90%的活检中检测到ecpvDNA,ecpv4是最常见的类型,其次是ecpv6,ecpv5,ecpv3和ecpv1.
- 在一个样本中单独检测到ecpv1,这挑战了之前关于其同时出现的发现.
结论:
- 巴西MM和QH马的耳斑普遍存在,MM马表现出更大的易感性.
- EcPV,特别是EcPV4,是听力斑块发展的一个重要因素.
- 需要对风险因素和病毒共感染进行进一步的研究.
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