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Updated: Jun 7, 2025

Real-time Imaging of Single Engineered RNA Transcripts in Living Cells Using Ratiometric Bimolecular Beacons
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Real-time Imaging of Single Engineered RNA Transcripts in Living Cells Using Ratiometric Bimolecular Beacons

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通过催化式头针组合的化传感器,用于精确的mRNA活细胞成像

Su-Jing Zhao1, Zhenkun Wu2, Jian-Hui Jiang1

  • 1State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biomedical Sciences, Hunan University, Changsha, China.

Methods in molecular biology (Clifton, N.J.)
|November 13, 2024
PubMed
概括

我们开发了一种新的化传感器,用于精确地对活细胞中与癌症相关的mRNA进行成像. 该工具具有高灵敏度和特异性,可以避免假阳性,从而改善癌症诊断和治疗.

关键词:
生物对等反应的生物对等反应生物传感器是一种生物传感器.催化式发针组件组件 催化式发针组件通过mRNA成像进行成像.

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相关概念视频

Reporter Genes02:11

Reporter Genes

Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
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