老年人中与功能相关的医疗保健费用:SCOPE研究
Francesco Balducci1, Mirko Di Rosa2, Regina Roller-Wirnsberger3
1Centre for Biostatistics and Applied Geriatric Clinical Epidemiology, Italian National Research Center on Aging (IRCCS INRCA), Ancona and Cosenza, Ancona, Italy.
European geriatric medicine
|November 13, 2024
概括
老年人患慢性病 (CKD) 的经济负担很大,主要是住院治疗和药物治疗. 管理并发症和功能衰退可以降低CKD患者的医疗费用.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 老年病的医生 老年病的医生
- 卫生经济学 卫生经济学
背景情况:
- 慢性病 (CKD) 在全球范围内构成重大经济挑战.
- 了解CKD的成本驱动因素对于资源配置和医疗保健政策至关重要.
研究的目的:
- 对慢性病 (CKD) 相关成本进行全面分析.
- 在多中心的国际环境中,确定影响CKD经济负担的因素.
主要方法:
- 这是一项为期两年的前性队列研究,涉及欧洲门诊诊所的75岁及以上的2204名受试者.
- 收集了资源消耗和单位成本的数据,以建立一个全面的成本数据库.
- 使用多级回归建模来分析人口统计,社会经济,临床和功能变量对成本的影响.
主要成果:
- 住院治疗,药物和专家访问是主要的成本驱动因素,国际差异很大.
- 估计的年度费用为4478欧元±9804欧元,增加到6683欧元±10,953欧元,对于估计的淋巴细胞过率 (eGFR) <30.
- 成本与疾病严重程度,性别,年龄和临床/功能共变量有显著的关联,即使考虑到国家间的差异.
结论:
- 对CKD患者来说,多维评估至关重要,因为多病态和功能障碍会对预后和护理成本产生负面影响.
- 保持功能能力和有效管理并发性疾病可以减少CKD患者,特别是老年人的医疗保健资源消耗.
相关概念视频
01:17Factors Affecting Renal Clearance: Renal Impairment
57
Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
57
01:11Renal Failure: Dose Adjustments
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In patients with renal impairment, drugs undergo significant changes in their pharmacokinetics, which require dosage adjustments to ensure safe and effective therapy.
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
67
01:45Kidney Structure
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The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
68.9K
01:27Dialysis
269
Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
269
01:02Renal Drug Excretion: Glomerular Filtration
170
The kidney serves as the primary organ responsible for eliminating drugs and their metabolites from the body. This process, known as renal elimination, starts with glomerular filtration and results in urine formation. Each kidney houses millions of functional units called nephrons, where urine production occurs. A nephron has two main components: a renal corpuscle and a renal tubule.
Drugs gain access to the kidney via the renal artery, which progressively branches off into afferent arterioles....
Drugs gain access to the kidney via the renal artery, which progressively branches off into afferent arterioles....
170
01:21External Anatomy of the Kidney
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The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
789