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胸膜厚度和视觉敏度在高近视没有近视性黄眼病:来自中国人口研究的见解

Yueye Wang¹, Decai Wang¹, Qiuxia Yin¹

¹State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China.

Translational vision science & technology

|November 13, 2024

概括

在高近视 (HM) 患者中,较薄的胸膜厚度 (ChT) 独立地与较差的最佳校正视敏度 (BCVA) 有关. 这一发现强调了CHT作为HM视力障碍的风险因素.

科学领域:

眼科医生眼科眼科
视网膜成像视网膜成像
近视研究近视研究

背景情况:

高近视 (HM) 对视力健康构成重大风险.
评估影响HM视力敏度的因素对于早期干预至关重要.
了解胸膜厚度 (ChT) 在没有黄斑病的HM中的作用是正在进行的研究领域.

研究的目的:

为了研究胆道厚度 (ChT) 和最佳校正视敏度 (BCVA) 之间的关联.
为了评估在被诊断为高近视 (HM) 但没有近视性黄眼病的患者中这种关联.

主要方法:

一项回顾性,横截面研究包括412名年龄在7至70岁之间的参与者,他们有双边HM.
扫描源光学连贯性断层扫描被用来测量亚叶 (SF) 胸腔.
线性回归模型分析了CHT和BCVA之间的关联,根据年龄,性别和轴长度进行调整.

主要成果:

与正常BCVA (176.74 ± 60.24) 相比,BCVA异常的参与者具有较薄的SF ChT (139.30 ± 58.63 μm).
在所有后极子区域中,较薄的CHT显著与更差的BCVA相关 (P<0.05).
最强的相关性是在外部下部区域;21微米的ChT稀释与BCVA的0.01恶化相对应,在40岁以上的男性中效果更强.

结论:

在没有近视性黄斑病的HM患者中,降低的ChT是BCVA恶化的独立预测因素.
在这个人群中,稀薄的CHT是不可逆转的视力敏度损伤的关键风险因素.

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