症状查与儿童癌症患者的护理途径相关:随机临床试验
L Lee Dupuis1,2, Emily Vettese1, Allison C Grimes3
1Program in Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Ontario, Canada.
JAMA
|November 13, 2024
概括
常规的症状查显著改善了儿童癌症患者的症状得分. 这种方法导致了更好的症状管理,但也增加了急诊室的访问.
科学领域:
- 儿童瘤学
- 治疗症状
- 临床试验
背景情况:
- 儿童癌症患者经常出现严重的症状.
- 常规症状查和治疗途径的有效性尚未得到充分证实.
研究的目的:
- 评估每周三次的症状查与反和管理护理途径是否改善了儿童癌症患者的症状得分,而不是通常的护理.
主要方法:
- 一个集群随机试验,涉及20个美国中心的445名儿童癌症患者 (8-18岁).
- 干预组每周接受三次症状查,警报和护理途径;对照组接受常规护理.
- 主要结局:儿童病症查工具 (SSPedi) 在8周的得分.
主要成果:
- 症状查组在8周后的SSPedi得分显著降低 (调整后的平均差异: - 3. 8).
- 在查组中,15个个体症状中有12个显著减少.
- 疲劳和生活质量没有差异;然而,查组的急诊室访问次数更多 (比率: 1.72).
结论:
- 用反和管理途径进行症状查可以改善儿童癌症患者的症状评分和干预措施.
- 建议将症状查纳入常规临床护理.
- 更多的紧急诊所需要进一步调查.
相关概念视频
Preventive Healthcare Services
972
Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
972
Cancer Survival Analysis
328
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
328
Combination Therapies and Personalized Medicine
4.9K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.9K


