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LI-RADS非辐射治疗响应算法版本2024:辅助特征的诊断性能和影响

Shuwei Zhou¹, Guofeng Zhou^2,3, Yang Shen⁴

¹Department of Radiology, Zhongda Hospital, Nurturing Center of Jiangsu Province for State Laboratory of AI Imaging & Interventional Radiology, School of Medicine, Southeast University, 87 Dingjiaqiao Rd, Gulou District, Nanjing 210009, China.

AJR. American journal of roentgenology

|November 13, 2024

概括

LI-RADS非辐射TRA v2024算法,结合辅助功能,证明了在地方区域疗法 (LRT) 后评估肝细胞癌 (HCC) 活力的提高灵敏度和准确性. 这种增强的方法有助于对HCC患者进行更好的预后评估和治疗决策.

科学领域:

肝胆道成像和干预
瘤成像和反应评估评估
肝癌的诊断和管理

背景情况:

肝脏成像报告和数据系统 (LI-RADS) 治疗响应算法 (TRA) 版本2024 (v2024) 引入了用于评估肝细胞癌 (HCC) 活力后辐射和非辐射局部治疗 (LRT) 的独特算法.
非辐射算法集成基于MRI的辅助功能,允许潜在的升级病变从LR-TR模糊到LR-TR可行的状态.

研究的目的:

将LI-RADS Nonradiation TRA v2024的诊断性能与LI-RADS TRA 2017 (v2017) 版本和修改后的RECIST (mRECIST) 进行比较,用于通过MRI评估HC对LRT的反应.
具体评估LI-RADS Nonradiation TRA v2024中的辅助功能对诊断性能的影响.

主要方法:

对231名患者 (平均年龄56岁) 的回顾性分析,这些患者在2017年1月至2022年12月期间接受了HCC的LRT,随后进行了肝切除或肝移植.
两位放射科医生独立地使用LI-RADS Nonradiation TRA v2024 (带有和没有辅助功能),LI-RADS TRA v2017和mRECIST评估了306个治疗的病变.
病理确认的病变活力 (n=249) 或亡 (n=57) 作为参考标准;LR-TR 模两可的评估被归类为测试负.

主要成果:

与没有辅助功能的相同算法相比,具有辅助功能的LI-RADS Nonradiation TRA v2024显示出更高的灵敏度和准确性 (两种读取器).
此外,该版本的灵敏度高于LI-RADS TRA v2017 (两种读取器),并且比mRECIST (两种读取器) 的特异性更高.
统计分析表明,当使用LI-RADS Nonradiation TRA v2024的辅助功能时,灵敏度和准确度显著提高.

结论:

LI-RADS非辐射TRA v2024在LRT后识别HCC病理生存能力方面表现出强大的诊断性能.
辅助特征的整合提高了灵敏度和准确性,而不会影响特异性,提供了更精细的评估.
更新的算法被推用于临床使用指导预后评估和治疗决策的HCC患者接受LRT.

关键词:

这就是为什么MRI是MRI.附属特征附属特征附属特征附属特征肝细胞癌是肝细胞癌.地方区域治疗方法.治疗反应治疗反应.

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