儿童发病的贝塞特病在年轻成年期的临床过程
Tugce Bozkurt1, Mehmet Yildiz2, Rabia Deniz3
1Department of Internal Medicine, Marmara University School of Medicine, Istanbul, Turkey.
儿科发病的贝塞特病 (BD) 可以导致新的主要器官感染或在成年后复发. 定期的成年人随访对于管理这种慢性疾病和预防长期损伤至关重要.
科学领域:
- 类风湿病学 类风湿病学
- 儿科医学 儿科医学
- 免疫学 免疫学 免疫学
背景情况:
- 贝塞特病 (BD) 通常在年轻人中出现,但发病可能发生在儿童时期.
- 儿科发病的BD可能会延长其全临床表现的发展.
- 评估童年开始的BD的长期结果对于患者管理至关重要.
研究的目的:
- 评估儿科发病的贝塞特病在年轻成年期的临床过程.
- 确定儿童发病BD.患者中主要器官参与和成人复发的频率.
主要方法:
- 五家三级诊所对112名18岁前被诊断患有BD的患者进行了回顾性分析.
- 纳入标准要求至少进行6个月的随访.
- 检查了临床表现,器官参与和疾病进展到成年期的数据.
主要成果:
- 该研究包括93名患有儿科发病的BD患者;64.5%是男性,中位数诊断年龄为15岁.
- 在儿童时期,52.5%的患者出现主要器官干扰,眼部干扰是最常见的 (29%).
- 在68名成人随访患者中,26.5%患有新的主要器官干扰,13.2%在成年后出现复发.
结论:
- 近三分之一的儿童发病BD患者在成年期经历了新的主要器官参与或疾病复发.
- 持续监测和定期跟踪儿童BD患者到成年至关重要.
- 积极主动的管理可以防止这种脆弱的患者群体的长期不可逆转的损害.
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