感染相关的慢性疾病:为什么长期的Covid是我们解开奥斯勒网络的最佳机会
Michael J Peluso1, Maureen R Hanson2, Steven G Deeks1
1Division of HIV, Infectious Diseases, and Global Medicine, University of California, San Francisco, San Francisco, CA 94110, USA.
Science translational medicine
|November 13, 2024
概括
长期Covid研究可以揭示其他感染相关的慢性疾病 (IACC). 一个协调的研究议程对于理解和解决这些使人衰弱的疾病至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 慢性疾病研究 慢性疾病研究
- 公共卫生 公共卫生
背景情况:
- 长期Covid的出现突出了更广泛的感染相关慢性疾病 (IACCs) 的类别.
- 关于各种IACC的现有研究提供了对长期Covid的潜在见解.
- 了解IACC中共享的机制和结果至关重要.
研究的目的:
- 探索长期Covid和其他IACC研究之间的协同关系.
- 倡导对这些条件采取统一的研究方法.
- 确定研究IACCs的共同挑战和机会.
主要方法:
- 文献综述和现有关于长期Covid和其他IACC研究的综合.
- 研究方法和研究结果的比较分析.
- 制定一个协调的研究议程的概念框架.
主要成果:
- 对长期Covid的研究可以为其他IACC的研究提供信息,反之亦然.
- 在不同的IACC中可以确定共享的研究问题和方法.
- 发现和治疗策略的交叉授粉的潜力.
结论:
- 协调的研究议程对于促进长期Covid和其他IACC的理解和管理至关重要.
- 跨学科的合作可以加速该领域的进展.
- 优先考虑IACC研究对于公共卫生和患者福祉至关重要.
相关概念视频
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
2.7K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Inflammation
2.7K
Infection
7.7K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
7.7K
Stages of Infection
55.6K
Stages of infection describe what happens to a susceptible host once a pathogen invades the human body. The stages of infection are incubation, prodromal, illness, stage of decline, and convalescence. The incubation stage is the period from exposure to a pathogen until symptoms start. The infected person is unaware of impending illness as the pathogens grow and multiply within the body. The duration may vary depending on the type of infection. The incubation period of measles averages ten to...
55.6K
Chronic Obstructive Pulmonary Disease-I: Introduction
2.8K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
2.8K
Chronic Bowel Disorders: Introduction
389
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
389
Factors Affecting the Risk of Infection
11.4K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.4K


