胃肠道功能障碍在COVID-19重病患者的预后意义
Ricardo Antônio Correia Lima1, Annika Reintam Blaser2, Júlia Falconiere Paredes Ramalho1
1Intensive Care Unit, Hospital Samaritano - Rio de Janeiro (RJ), Brazil.
严重病情的COVID-19患者的胃肠道功能障碍,通过评分系统进行评估,预测了更糟糕的住院和1年的结果,包括死亡率和需要机械通风.
科学领域:
- 关键护理医学 关键护理医学
- 传染性疾病 传染性疾病
- 胃肠病学 胃肠病学
背景情况:
- 患有COVID-19的重症患者经常经历胃肠道功能障碍.
- 评估胃肠功能障碍的严重程度对于预测患者的结果至关重要.
研究的目的:
- 在重症COVID-19患者中分析与急性胃肠道功能障碍相关的住院和1年的发病率和死亡率.
- 评估预先规定的胃肠道损伤评分系统的预测价值.
主要方法:
- 对2020年3月至7月期间入院的215名危急COVID-19患者的回顾性分析.
- 胃肠道功能障碍在前7天内使用5分渐进性损伤评分系统进行评估.
- 收集的数据包括实验室结果,并发病,机械通风,ICU停留和死亡率.
主要成果:
- 胃肠道功能障碍存在于20.9%的患者中,与更长的ICU住院和更高的C-反应蛋白水平有关.
- 胃肠功能障碍得分显著预测死亡率 (OR 2.8) 和需要机械通风 (OR 2.8).
- 住院和1年死亡率随着胃肠功能障碍得分的提高而逐渐增加.
结论:
- 在重症COVID-19患者中,胃肠道功能障碍的严重程度是不良结果的重要预测因素.
- 预先规定的评分系统有效地识别出患有住院和1年死亡风险较高的患者.
- 早期评估胃肠道功能障碍可能有助于对COVID-19患者的风险分层和管理.
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