治疗高甲血症是否会影响怀孕和围产期的结果?
Amanda Carvalho Santos1, Daniela Angerame Yela1,2, Renan Massao Nakamura1,2
1University of Campinas, School of Medicine - Campinas (SP), Brazil.
概括
孕妇的高血性乳腺血症不会影响产科的结果,无论他们是否接受了卡伯戈林或布罗莫克里普丁治疗. 这项研究在治疗组之间发现了类似的怀孕和分娩并发症率.
科学领域:
- 内分泌学 在内分泌学.
- 产科和妇科 产科和妇科
- 生殖医学 生殖医学
背景情况:
- 超益生菌性血症 (hyperprolactinemia) 是一种因益生菌素水平升高而表现的疾病,可能会影响生殖健康.
- 多巴胺激动剂,如卡伯戈林和烯,通常用于治疗高血糖性血症.
- 了解不同治疗对怀孕结果的影响对于患者管理至关重要.
研究的目的:
- 根据他们使用卡伯戈林或烯的治疗,比较孕妇患有高血糖性血症的产科和周产期结局.
- 为了确定使用的多巴胺激动剂类型是否会影响怀孕并发症或分娩结果.
主要方法:
- 一项回顾性队列研究包括了464名被诊断患有高甲血症的妇女,接受了多巴胺激动剂治疗.
- 孕妇 (n=72) 根据治疗方式被分为两组:布罗莫克里普丁或卡伯戈林.
- 评估了产科和产周结局,包括怀孕和产后并发症.
主要成果:
- 在接受烯与卡伯戈林治疗的妇女之间没有观察到产科结果的显著差异.
- 大多数妇女经历了无并发症的怀孕 (76.3%) 和产前期 (86.8%).
- 异常性超生菌血症更频繁地用布罗莫克里普丁治疗,而瘤性超生菌血症更频繁地用卡伯戈林治疗 (p=0.04).
结论:
- 过高乳糖血症似乎不会对孕妇的产科结果产生负面影响.
- 之前的多巴胺激动剂治疗类型 (cabergoline或bromocriptine) 并没有改变怀孕或分娩的结果.
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