部分肝切除术后胃肠功能延迟恢复:单中心横截面研究
Giulia Piazza1, Ismail Labgaa2, Emilie Uldry2
1Department of Visceral Surgery, Lausanne University Hospital CHUV, University of Lausanne (UNIL), Lausanne, Switzerland, gipiazza13@gmail.com.
Digestive surgery
|November 13, 2024
概括
部分肝切除术 (PH) 后胃肠功能延迟恢复 (DRGF) 影响了16%的患者. 更长的手术持续时间,主要的PH,以及术后的双瘤/胆道泄漏是DRGF和长时间住院的关键预测因素.
科学领域:
- 肝胆道手术 肝胆道手术
- 胃肠道生理学 胃肠道生理学
- 手术结果研究研究.
背景情况:
- 部分肝切除术 (PH) 与显著的并发症率 (30-50%) 有关.
- 胃肠功能延迟恢复 (DRGF) 影响10-20%的PH后患者.
- 识别DRGF预测因子对于改善PH后患者康复至关重要.
研究的目的:
- 为了确定PH后DRGF的发病率.
- 确定与DRGF相关的独立预测因素.
- 为优化PH患者手术后康复的策略提供信息.
主要方法:
- 在2010-2019年间,对501名接受PH的成年患者进行了回顾性分析.
- DRGF定义为术后鼻胃管 (NGT) 插入的需要.
- 多变量逻辑回归用于识别独立的DRGF预测器.
主要成果:
- DRGF发生在16%的患者中,与更长的住院时间有关.
- 最少侵入性的方法显示DRGF率显著降低 (4.5%与19.8%相比).
- 确定了独立的预测因素:较长的手术持续时间,主要的肝切除术和术后的双瘤/胆道泄漏.
结论:
- 在PH之后,DRGF是一种显著的并发症,影响了16%的患者.
- 更长的手术持续时间,主要的PH和术后的双瘤/胆道泄漏是DRGF的独立预测因素.
- 这些发现突出了管理和潜在地预防PH后DRGF的关键因素.
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