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Updated: Jun 27, 2026

A Piglet Model of Neonatal Hypoxic-Ischemic Encephalopathy

A Piglet Model of Neonatal Hypoxic-Ischemic Encephalopathy

Published on: May 16, 2015

评估新生儿脑病导致的全球负担:经济评估

Ramesh Vidavalur¹, Kiran More², Vinod K Bhutani³

¹Department of Neonatology, Cayuga Medical Center, Weill Cornell Medicine, Ithaca, NY, USA.

Seminars in fetal & neonatal medicine

|November 13, 2024

概括

新生儿脑病变 (NE) 在低收入国家造成大量死亡和经济损失. 有针对性的战略和更好的资源配置对于降低NE负担和改善结果至关重要.

科学领域:

公共卫生公共卫生
全球卫生经济学全球卫生经济学
新生儿医学新生儿医学

背景情况:

新生儿脑病变 (NE) 是低收入和中等收入国家 (LMICs) 新生儿死亡的主要原因.
对于对资源分配至关重要的新能源的经济影响数据有限.
了解NE的经济负担对于确定公共卫生优先事项至关重要.

研究的目的:

估计2019年死亡人数最高的十个国家中NE的特定国家疾病和经济负担.
分析NE特定的死亡率趋势并计算失去了生命年 (YLLs).
通过使用统计寿命值 (VSL) 和统计寿命年值 (VSLY) 方法来评估经济损失.

主要方法:

利用了来自全球疾病负担 (GBD) 协作网络的数据.
分析了NE特定的死亡率趋势,并使用预期寿命计算了YLL,使用或不使用年龄加权和折扣.
采用VSL和VSLY的经济损失评估方法,包括使用可变贴现率的灵敏度分析.

主要成果:

2019年,在十大负担国家中,估计有138,763例新生儿死亡归因于NE.
年终收入在450万 (有折扣) 到980万 (没有折扣) 之间.
经济损失估计为800亿美元 (VSL) 和7200亿美元 (VSLY).

结论:

尽管新生儿死亡率总体下降,但10个负担最高的国家中有6个在2010-2019年间经历了NE特定死亡率的上升.
需要有针对性,有资金的战略来打击LMICs的NE.
改善产前护理,分娩周边实践和资源配置可以显著降低NE的负担.

关键词:

根据残疾调整的寿命年数.经济评估经济评价医疗保健成本医疗保健成本低收入和中等收入国家.新生儿脑病变新生儿脑病变每个统计寿命的值.每个统计寿命年值.

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