低骨矿物质密度与50岁以上女性的高频听力障碍有关:韩国的一项观察性研究
Sang-Hoon Lee1, Seung-Soo Lee2, Hun-Yi Park3
1Department of Family Medicine and Functional Medicine, Greencross I-MED Gangnam Medical Clinic, Seoul, Korea.
Korean journal of family medicine
|November 13, 2024
概括
骨质疏松症与50岁以上女性的听力损失有关,特别是在高频率时. 这种关联在男性中没有发现,这突出了骨密度和听觉健康之间的性别特异关系.
科学领域:
- 老年学是一门学科.
- 听力学 听力学是指听力学.
- 骨质疏松症研究 骨质疏松症研究
背景情况:
- 骨质疏松症和听力障碍是已知的健康问题,有潜在的联系.
- 之前的研究还没有明确定义特定性别的关联或骨矿物质密度 (BMD) 和听力损失频率的特定测量地点.
研究的目的:
- 在50岁以上的成年人中调查听力损失和BMD之间的关系.
- 为了确定与骨质疏松症相关的特定纯音声听力测试 (PTA) 频率.
- 确定相关的BMD测量地点,并探索这些协会中的性别差异.
主要方法:
- 一组1523名50岁以上的成年人 (651名男性,872名女性) 接受了医疗健康检查.
- 纯音调听力测量 (PTA) 评估了听力功能.
- 双能X射线吸收计测量了腰椎 (LV) 和大腿骨的骨矿物质密度 (BMD).
主要成果:
- 在女性 (P<0.01) 中发现听力障碍和骨质疏松症之间存在显著的关联,但在男性中没有.
- 在女性中,腰部BMD (L1-4) 与4000Hz和8000Hz (P<0.05) 的听力损失有显著的相关性.
- 后勤回归证实,骨质疏松症增加了女性在4,000 Hz (OR, 2.078) 和8,000 Hz (OR, 2.648) 听力损失的几率,即使经过对共变量进行调整.
结论:
- 腰部下部BMD与50岁以上女性的听力损伤有显著的关联.
- 这种联系在高听力频率 (4,000和8,000赫兹) 尤其明显.
- 研究结果表明,骨质疏松症和高频听力损失之间存在特定性别的联系.
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