慢性腹痛患者的炎症性肠病缓解期:临床医生的持续挑战
Natasha Klemm1, Sarvee Moosavi2
1Department of Gastroenterology, University of British Columbia, Vancouver, V5Z 1M9, Canada. nklemm@alumni.ubc.ca.
慢性腹痛在炎症性肠病 (IBD) 患者中很常见,即使在缓解期. 本综述侧重于管理肠-大脑相互作用障碍和其他导致静止IBD疼痛的原因.
科学领域:
- 胃肠病学 胃肠病学
- 神经胃肠病学 神经胃肠病学
- 慢性疼痛管理 慢性疼痛管理
背景情况:
- 炎症性肠病 (IBD),包括性结肠炎和克罗恩病,是一种影响生活质量的慢性疾病.
- 尽管得到缓解,但许多IBD患者经历了持续的腹痛.
- 可能的原因包括手术史,感染,盆腔问题,免疫因素,全身疾病和肠-大脑相互作用 (DGBI) 障碍.
研究的目的:
- 审查有关静止IBD患者慢性腹痛管理的文献.
- 探索DGBI在IBD相关的腹痛中的作用.
- 讨论在IBD中治疗慢性腹痛的治疗策略.
主要方法:
- 对IBD中慢性腹痛研究的文献综述.
- 专注于识别病因和管理策略.
- 在静止的IBD中强调DGBI.
主要成果:
- 慢性腹痛是IBD患者常见的,通常是孤立的症状.
- 越来越多地认识到DGBI是静止IBD腹痛的重要贡献者.
- 目前正在研究非药物治疗和药物治疗.
结论:
- 在IBD中有效管理慢性腹痛需要全面的方法.
- 解决DGBI对于改善患者治疗结果至关重要.
- 对静止IBD疼痛的治疗干预措施的进一步研究是有必要的.
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