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Updated: Jun 7, 2025

In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones
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通过Polycomb抑制复合体1进行H2A无处置的读写机制

Victoria Godínez López1, Marco Igor Valencia-Sánchez1, Stephen Abini-Agbomson1

  • 1Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, USA.

Nature
|November 13, 2024
PubMed
概括

非正规的Polycomb抑制复合体1 (ncPRC1RYBP) 通过一种新型的读写机制恢复了基因组H2AK119单化 (H2AK119Ub),确保了胚胎发生期间的细胞记忆.

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