接近于赤道几内亚的霍乱消除:几乎零传播和公共卫生影响
Policarpo Ncogo1,2,3, Ana Hernández-González4,5, Thuy-Huong Ta-Tang2,5
1National Onchocerciasis and Other Filariasis Control Programme. Ministry of Health, Malabo, Equatorial Guinea.
Infectious diseases of poverty
|November 13, 2024
概括
在赤道几内亚,瘤病的传播不再是公共卫生问题,接近消除. 淋巴状病 (LF) 的流行率被绘制为指导国家根除战略.
科学领域:
- 热带医学 热带医学
- 传染性疾病 传染性疾病
- 寄生虫学的寄生虫学
背景情况:
- 瘤病和淋巴状病 (LF) 是赤道几内亚的特有病,历史上控制工作集中在比奥科岛.
- 之前在赤道几内亚大陆进行的地图绘制显示了关于LF和肉病传播水平的不确定的结果.
- 鉴于在比奥科岛的氏球菌病中断,评估大陆当前的疾病状况至关重要.
研究的目的:
- 更新厄瓜多尔几内亚大陆肉病和LF的流行率估计.
- 利用各种诊断技术进行准确的疾病评估.
- 为国家消除 filariasis 的战略提供信息.
主要方法:
- 在赤道几内亚大陆 (2019年9月至12月) 进行的第一个横截面研究.
- 采用了皮肤切片活检,厚血涂抹,ELISA (Ov16,Wb123) 和分子测试.
- 计算频率,流行率和95%的置信区间.
主要成果:
- 瘤瘤病的血清流行率为0.3%;显微镜检测是负的,但通过测序确认了一例阳性病例.
- 淋巴性 filariasis (抗Wb123抗体) 的血清流行率为4.6%.
- 对W. bancrofti的显微镜和F-RT-PCR在所有样本中均呈阴性.
结论:
- 在赤道几内亚,瘤病不太可能成为公共卫生问题,这表明在消除方面取得了进展.
- 该研究提供了对LF的重要流行数据,有助于国家根除计划.
- 这些发现支持了在全国范围内消除 filariasis 的潜力.
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