相关实验视频

Updated: Jun 7, 2025

Targeted DNA Methylation Analysis by Next-generation Sequencing
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Targeted DNA Methylation Analysis by Next-generation Sequencing

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DNA甲基化生物标志物和近视:一个整合GWAS,mQTL和eQTL数据的多omics研究

Xing-Xuan Dong1, Dong-Ling Chen1, Hui-Min Chen1

  • 1School of Public Health, The Fourth Affiliated Hospital of Soochow University, Suzhou Medical College of Soochow University, Suzhou, China.

Clinical epigenetics
|November 14, 2024
PubMed
概括

这项研究使用基于总结数据的门德尔随机化 (SMR) 确定了六种与近视风险相关的DNA甲基化生物标志物. 这些发现可能有助于理解近视.

关键词:
生物标志物生物标志物通过DNA甲基化.门德尔的随机化多个omics的多个omics.近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近

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相关概念视频

Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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