预防和管理偏头痛发作的实用补充剂:叙事性综述
Zahra Hajhashemy1,2, Sahar Golpour-Hamedani1,2, Niloofar Eshaghian1,2
1Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran.
Frontiers in nutrition
|November 14, 2024
概括
某些营养补充剂,包括 рибофлавин 和,可能有助于预防和管理偏头痛发作. 这些饮食干预措施针对氧化应激和炎症等潜在机制,为偏头痛患者提供潜在的缓解.
科学领域:
- 神经学 神经学
- 营养科学 营养科学
- 生物化学 生物化学
背景情况:
- 偏头痛是一种流行的神经系统疾病,影响全球11%的人口,其特点是令人虚弱的头痛.
- 营养素缺乏与偏头痛频率和严重程度的增加有关.
- 了解营养素的作用对于偏头痛管理至关重要.
研究的目的:
- 审查用于偏头痛预防和管理的实用食补充剂.
- 为了确定对偏头痛有潜在治疗作用的关键营养素.
主要方法:
- 从主要科学数据库 (PubMed,科学网络,EMBASE,Scopus,谷歌学者) 的研究进行叙事审查.
- 收录标准:英语文章,成人人口 (>18岁),重点是营养补充和偏头痛症状.
- 搜索术语包括"食补充剂"和"偏头痛"及其MeSH术语,直到2024年7月27日.
主要成果:
- 氧化应激和低抗氧化剂摄入量通过炎症和细胞因子释放 (例如TNF-a) 导致偏头痛.
- 偏头痛与CGRP,线粒体功能障碍,大脑能量代谢的改变,以及高谷氨酸和同氨酸水平有关.
- 补充支持线粒体功能,能量代谢和甲基化的营养素可以缓解偏头痛.
结论:
- 证据支持利博弗拉,欧米茄-3脂肪酸,α-酸,,益生菌,辅酶Q10,生和咖啡因对偏头痛患者的有益作用.
- 需要进一步的前性研究来确认这些和其他营养素的有效性.
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