儿科系统性炎症反应综合征 (SIRS) 和患者特异性治疗的发展:通过专家意见的伦理观点
Frederik Stolte1, Silviya Aleksandrova-Yankulovska1, Paul Thiemicke1
1Institute of the History, Philosophy and Ethics of Medicine, Ulm University, Ulm, Germany.
Frontiers in public health
|November 14, 2024
概括
在使用OMICS和AI的儿童中,针对系统性炎症反应综合征 (SIRS) 的个性化疗法存在道德挑战. 专家建议采用一种支持性方法,包括跨学科的合作,并为医生和人工智能开发人员提供增强的培训.
科学领域:
- 儿科急救医学 儿科急救医学
- 生物伦理学生物伦理学
- 医疗信息学 医疗信息学
背景情况:
- 针对儿童系统性炎症反应综合征 (SIRS) 的个性化疗法利用OMICS技术和人工智能 (AI).
- 在将这些先进技术整合到儿科研究中时,道德考虑至关重要.
研究的目的:
- 从医疗保健专业人员的角度确定个性化SIRS研究中的特定伦理挑战.
- 在此背景下探索知情同意,数据处理和社会正义的复杂性.
主要方法:
- 与儿科重症监护,计算机科学和医疗法专家进行了10次半结构面试.
- 利用系统的文献审查来为面试问题开发提供信息.
- 使用已确定的内容和主题分析指南分析了定性数据.
主要成果:
- 受访者强调,由于复杂的信息要求,在管理知情同意方面存在困难.
- 人们对数据匿名化,保护和研究群体潜在的偏见表示担忧.
- 专家们主张在儿科SIRS研究中使用AI和OMICS.
结论:
- 个性化SIRS治疗的伦理和法律挑战正在不断发展,需要持续讨论.
- 应该重新考虑监管模式,超越纯粹的预防原则.
- 建议包括加强跨学科培训和医生,人工智能开发人员和法律专家之间的合作.
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