截然不同的构造在中风后的患者报告和绩效评估结果的基础上
Julie A DiCarlo1,2, Abhishek Jaywant3, Perman Gochyyev4
1Center for Neurotechnology and Neurorecovery, Department of Neurology, Massachusetts General Hospital, Boston, MA.
Annals of neurology
|November 14, 2024
概括
患者报告的结果 (PROM) 和中风幸存者的绩效指标是不同的. 社会人口学因素和头顶叶损伤影响PROMs,而皮质脊柱管损伤影响表现结果.
科学领域:
- 神经学 神经学
- 神经康复疗法 神经康复疗法
- 临床结果研究研究
背景情况:
- 患者报告结果指标 (PROM) 在神经学研究中至关重要,但它们与基于绩效的指标的关系尚未完全理解.
- 社会人口结构因素和脑损伤位置,特别是在自我意识区域,可能会影响PROMs.
研究的目的:
- 研究中风幸存者与手臂运动障碍之间的PROMs和基于绩效的措施之间的关系.
- 确定社会人口学因素和神经解剖学对这些不同的结果类的影响.
主要方法:
- 54名中风幸存者的纵向评估,使用患者报告和绩效评级的措施,跨越4个时间点.
- 用因子分析来定义结果结构,用线性回归来确定社会人口统计学关联,用语音损伤-症状/网络绘制来确定神经解剖相关性.
主要成果:
- 基于绩效和患者报告的措施在整个康复过程中形成了不同的因素.
- 高等教育和收入充足程度与PROM相关,而不是绩效指标.
- 叶损伤与更糟糕的PROM有关,而皮质脊柱管损伤与更糟糕的表现结果有关. Salience 网络连接也影响了 PROM.
结论:
- 在中风后的绩效评级和患者报告结果之间存在显著差异,每个结果都与独特的因素和脑损伤模式有关.
- 将社会人口统计和神经解剖学数据整合到神经康复中可能会改善患者的治疗结果.
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