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Updated: Jun 7, 2025

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
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在小鼠和猪中进行外周介导的阿片类药物联合治疗

C D Peterson1, C M Larson2, D J Bruce3

  • 1Department of Pharmaceutics, University of Minnesota College of Pharmacy, USA; Department of Neuroscience, University of Minnesota Medical School, USA; Department of Experimental and Clinical Pharmacology, University of Minnesota College of Pharmacy, USA.

The journal of pain
|November 14, 2024
PubMed
概括

新型阿片类药物组合,洛佩拉米德与氧化或N-基-氧化,在小鼠和猪中提供协同作用的疼痛缓解. 这些疗法针对μ-和δ-阿片类受体,减少过敏症,没有不良影响.

关键词:
止痛药 止痛药是一种止痛药.组合协同效应 组合协同效应洛佩拉米德的使用方法氧化物形态斗 (oxymorphindole) 是一种氧化物形态斗.猪模型 猪模型

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