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Updated: Jun 7, 2025

Spatiotemporal Control of Protein Activity through Optogenetic Allosteric Regulation
08:00

Spatiotemporal Control of Protein Activity through Optogenetic Allosteric Regulation

Published on: October 4, 2024

504

通过ssDNA结合和局部电荷变化对Lon蛋白酶的Allosteric调制

Justyne L Ogdahl1, Peter Chien1

  • 1Department of Biochemistry and Molecular Biology, Molecular and Cellular Biology Program, University of Massachusetts, Amherst, USA.

The Journal of biological chemistry
|November 14, 2024
PubMed
概括

单链DNA (ssDNA) 结合通过增强ATP水解和蛋白质降解来激活Lon蛋白酶. 电荷突变模仿了这种ssDNA激活,揭示了Lon蛋白酶活动的静电调节.

关键词:
这是一种依赖ATP的蛋白酶.亚太酶 ATPase 是一种酶.结合 DNA 的 DNA 结合.艾洛斯特菌是所有菌的单蛋白酶是一种蛋白质酶.质量测光仪的质量测光仪.

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