呈现效应的巨细胞瘤的临床特征和荷尔蒙特征:系统性审查
Muhannad M Mahmoud1, Laith M Haj-Ahmad1, Nabil William G Sweis1
1School of Medicine, The University of Jordan, Amman, Jordan.
概括
效应可能会导致巨型巨瘤患者的错误低血清素水平. 稀释研究对于在 pituitary macroadenoma 病例中准确诊断至关重要.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 临床化学 临床化学
背景情况:
- 效应是一种测试工件,导致虚假的低血清益乳素测量.
- 巨细胞瘤, pituitary 瘤产生前素,可以受到这种人工物的影响.
- 精确的益乳素测量对于诊断和管理这些瘤至关重要.
研究的目的:
- 系统地审查和描述与被诊断为巨细胞巨瘤的患者的效应相关的临床特征.
- 为了确定常见的患者和瘤特征,在表现出效应的巨乳细胞瘤病例中.
主要方法:
- 在多个数据库中进行了系统的搜索,寻找病例报告,病例系列和效应的巨型巨瘤的观察性研究.
- 包括来自机构案件的数据.
- 为了分析,提取了患者和瘤的特征.
主要成果:
- 分析了61名患有巨细胞巨瘤和效应的患者.
- 常见的症状包括眼科问题 (80.9%) 和头痛 (66.0%).
- 相关的垂体荷尔蒙缺乏症是中央下腺症 (63.6%) 和中央甲状腺功能低下症 (44.1%).
结论:
- 具有效应的巨细胞瘤的临床表现与没有效应的巨细胞瘤相似.
- 对于所有患有脑垂体宏腺瘤的患者,表现出正常或轻微升高的血清前素水平,对前素的稀释研究至关重要.
- 这凸显了识别和减轻测试文物对于正确的临床管理的重要性.
相关概念视频
Major Hormones and Their Functions
333
Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
333
Drugs Affecting GI Tract Motility: Dopamine Receptor Antagonists
260
Prokinetic agents are specialized medications that stimulate gastrointestinal (GI) motility, promoting food movement through the GI tract. Dopamine, an inhibitory neurotransmitter, plays a significant role in this process, reducing GI motility and indirectly controlling the speed of digestion. Dopamine receptor antagonists, such as metoclopramide and domperidone, offer a unique advantage as prokinetic agents. By blocking the dopamine receptors, these drugs increase GI motility, improving food...
260
Hormones of the Pituitary Gland
6.3K
The small, pea-sized pituitary gland is located at the base of the brain. It is crucial in regulating various bodily functions, from growth to reproduction. The gland is divided into the anterior lobe and the posterior lobe. The secretory cell clusters in the pars distalis of the anterior pituitary lobe are controlled by hypothalamic regulators and synthesize six primary hormones.
The most abundantly secreted hormone from the anterior lobe is the growth hormone, which controls overall growth by...
The most abundantly secreted hormone from the anterior lobe is the growth hormone, which controls overall growth by...
6.3K
Regulation of Hormone Secretion
3.2K
Regulation of hormone secretion is a finely tuned orchestration driven by various types of stimuli, encompassing neural, humoral, and hormonal signals. Environmental cues instigate neural stimuli, where action potentials traverse nerve fibers to reach their designated targets. An illustrative scenario is the body's response to stress, wherein the sympathetic nervous system releases epinephrine from the adrenal glands, inducing the well-known 'fight or flight' reaction.
Humoral...
Humoral...
3.2K
Hormonal Regulation of the Menstrual Cycle
297
The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
297
Feedback Loops
56.5K
In most cases, excessive hormone production is prevented by negative feedback—a loop that starts with a stimulus inducing the release of a particular substance, like a hormone, to maintain a certain level before triggering a signal that results in a decrease in further release of the hormone.
56.5K


