间海马体粘附:在接受MRI的儿科患者中,患病率,结构和基于位置的分类图
Michael P Oien1, Onur Tuncer2, David Nascene3
1Mayo Clinic Department of Radiology, Mayo Building West, 2nd Floor 200 First St. SW, Rochester, MN, 55905, USA.
Neuroradiology
|November 14, 2024
概括
皮质体间粘附 (IHA) 发生在2.13%的儿科患者中,并且通常会随着时间的推移而持续. 这些粘附显示灰色物质信号强度,与3型IHA与垂体异常有关.
科学领域:
- 儿科神经放射学 儿科神经放射学
- 神经成像是一种神经成像.
- 内分泌学 在内分泌学.
背景情况:
- 间位粘附 (IHA) 是一种罕见的发现,主要在儿科患者中报告.
- 它们的患病率,持续性和精确的组织学组成在很大程度上仍未被描述.
- 了解IHA对于诊断相关的神经和内分泌疾病至关重要.
研究的目的:
- 为了确定小儿大脑MRI研究中IHA的患病率.
- 通过纵向成像来评估IHA的持续性.
- 根据解剖分布对IHA进行分类,探索其成像特征,并确定相关的病理.
主要方法:
- 对儿科大脑MRI扫描 (2012-2013) 的回顾性审查.
- 在至少两个成像平面上确认IHA.
- 测量IHA截面面积和信号强度 (T2WIs),对白色和灰色物质信号进行规范化.
- 收集患者的人口统计和临床信息.
主要成果:
- 确定了2.13% (33/1550名患者) 的IHA患病率.
- 在92%的随访扫描中,IHA显示持久性.
- 正常化的IHA信号强度与灰质 (r=0.83,P<0.001) 有很强的相关性,但与白质 (r=-0.16,P=0.494) 没有很强的相关性.
- 常见的相关病理包括水头发症 (9),早产 (8),体异常 (7).
- 所有3型IHA (3/3) 都与下垂体病理有关.
结论:
- 在儿科队列中,IHA在2.13%的人群中存在,并且在很大程度上是持久的.
- 在MRI上,IHA信号强度反映了灰色物质的信号强度.
- 3型IHA仅与垂体异常有关,突出显示了它们的临床意义.
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