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Updated: Jun 7, 2025

Detection of RNA-binding Proteins by In Vitro RNA Pull-down in Adipocyte Culture
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Detection of RNA-binding Proteins by In Vitro RNA Pull-down in Adipocyte Culture

Published on: July 22, 2016

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DHX36结合诱导RNA结构体重塑,并通过m6调节RNA的丰富性阅读器YTHDF1

Yuwei Zhang1, Jieyu Zhao2, Xiaona Chen3,4

  • 1Department of Chemical Pathology, Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, Hong Kong, SAR, China.

Nature communications
|November 14, 2024
PubMed
概括

DEAH盒酶36 (DHX36) 蛋白重塑RNA结构,特别是在3'未翻译区域 (3'UTR). 这种结构变化增强了N6-甲基氨酸 (m6A) 修饰和YTHDF1结合,最终降低了mRNA的丰度.

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