在老年患者中,生命的基本8和认知障碍之间的关联:NHANES 2011-2014年的结果
Hui Wang1, Sensen Wu1, Dikang Pan1
1Department of Vascular Surgery, Xuanwu Hospital, Capital Medical University, No. 45, Changchun Street, Beijing, Beijing, 100053, China.
BMC geriatrics
|November 15, 2024
概括
美国心脏协会对生活必需8 (LE8) 改善心血管健康 (CVH) 的更高坚持与老年人认知障碍的几率降低有关.
科学领域:
- 老年学是一门学科.
- 心血管健康 心血管健康
- 神经科学是一个神经科学.
背景情况:
- 美国心脏协会 (AHA) 推出了生命必不可少的8 (LE8) 算法来评估心血管健康 (CVH).
- 认知障碍在老年人群中越来越令人担忧.
- 修订后的CVH指标与老年人认知功能之间的关系需要进行调查.
研究的目的:
- 为了检查AHA的Life's Essential 8 (LE8) 算法与美国老年人的认知障碍之间的关联.
- 为了确定较高的心血管健康得分是否与较低的认知衰退发病率相关.
- 通过改变生活方式,提供对认知障碍的预防策略的见解.
主要方法:
- 使用国家健康和营养检查调查 (2011-2014) 数据进行的横截面研究.
- 用AHA的LE8来评估心血管健康 (CVH),分为低级,中级和高级.
- 认知障碍通过CERAD,动物流利性测试 (AFT) 和数字符号替换测试 (DSST) 进行评估,通过后勤回归和受限制立方线模型进行分析.
主要成果:
- 在LE8得分和认知障碍之间观察到显著的负相关性.
- 在所有测试的认知指标 (CERAD,AFT,DSST) 中,较高的CVH (LE8) 与认知障碍的几率显著降低有关.
- 限制性立方线分析揭示了LE8定义的生活方式因素和认知障碍之间的线性关系.
结论:
- 越来越多地遵守LE8指南,表明更好的CVH,与认知障碍的可能性降低有关.
- 保持最佳的心血管健康是预防老年人认知能力下降的关键因素.
- LE8算法是评估风险和促进老年人群中大脑健康的宝贵工具.
相关概念视频
Cognitive Development During Adulthood
58
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
58
Alzheimer's Disease: Overview
448
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
448
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists
98
Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
98
Dementia
97
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
The progression of dementia is generally gradual....
97


