心脏代谢指数与女性不孕症之间的相关性:一个横截面分析
Yiran Zhao1,2, Weihui Shi1,2, Yang Liu1,2
1Obstetrics and Gynecology Hospital, Institute of Reproduction and Development, Fudan University, Shanghai, China.
Reproductive biology and endocrinology : RB&E
|November 15, 2024
概括
更高的心脏代谢指数 (CMI) 与女性不孕症风险增加有关. 这项研究强调CMI是美国女性不孕症的潜在预测因素,强调了代谢健康和生殖结果之间的联系.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 心血管健康 心血管健康
- 代谢综合征是代谢综合征的一种.
背景情况:
- 肥胖和异常的脂质样本已知是导致女性不孕症的因素.
- 心脏代谢指数 (CMI) 显示了预测与肥胖有关的疾病的潜力.
- CMI与女性不孕症之间的关系需要进一步研究.
研究的目的:
- 调查心脏代谢指数 (CMI) 和女性不孕症之间的相关性.
- 评估CMI对美国女性不孕症的预测价值.
主要方法:
- 利用了2013-2020年国家健康和营养检查调查 (NHANES) 的数据.
- 使用甘油三,高密度脂蛋白胆固醇和腰与身高的比率计算CMI.
- 使用加权多变量逻辑回归和子组分析来评估CMI和不孕症之间的关联.
主要成果:
- 在较高的CMI水平和不孕症风险增加之间观察到显著的正相关性 (OR = 2.411).
- 这种关联在35岁以下的女性中保持一致.
- 限制性立方脊线分析显示,CMI和不孕症之间存在积极的非线性关系.
结论:
- 心脏代谢指数 (CMI) 水平升高与美国女性不孕症风险更高有关.
- CMI证明了女性不孕症的预测能力,强调了其临床相关性.
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