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粘弹性血液静止试验以指导选择性外科手术的治疗:更新的系统综述和元分析
Joao D Dias1, Jerrold H Levy2, Kenichi A Tanaka3
1Haemonetics SA, Signy, Switzerland.
Anaesthesia
|November 15, 2024
概括
粘弹性血液静止试验 (VHA) 在重大选择性手术中显著减少了血液产品输血和血液损失. 虽然VHA在治疗外科手术前出血方面有效,但对患者为中心的死亡率等结果没有影响.
科学领域:
- 麻醉学和重症监护医学
- 血液学 血液学 血液学
- 手术科学 手术科学
背景情况:
- 严重的失控出血是接受重大手术的患者的重大风险.
- 粘弹性静血试验 (VHA) 越来越多地用于指导输血策略.
- 本系统性综述和元分析评估了VHA在选择性手术期间管理术后出血的临床疗效.
结论:
- 粘性弹性血静定量导向疗法在减少外科手术期间输血和大选手术期间的血液损失方面表现有前途.
- 目前的证据表明,VHA导向治疗没有明显影响以患者为中心的结果.
- 支持这些发现的证据的整体质量是温和的.
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